BDBM50358609 CHEMBL1921858

SMILES CC[C@H]1CN(CCN1C2CCN(CC2)Cc3ccc(cc3)Cl)c4c(nc(c(n4)N)C(=O)N)Cl

InChI Key InChIKey=UYDYJFWSPRQEAX-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50358609   

TargetC-X-C chemokine receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataIC50: 0.800nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to CXCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)