BDBM50356915 GANODERIC ACID B

SMILES C[C@H](CC(=O)CC(C)C(O)=O)[C@H]1CC(=O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1C[C@@H]3O

InChI Key InChIKey=LWPLEHFGBRFRKI-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50356915   

TargetTumor necrosis factor(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50356915(GANODERIC ACID B)
Affinity DataKd:  8nMAssay Description:Binding affinity to TNF-alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50356915(GANODERIC ACID B)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of AChE assessed as hydrolysis of acetylcholine preincubated for 15 mins measured after 15 mins by colorimetric Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50356915(GANODERIC ACID B)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of BChE assessed as hydrolysis of butrylcholine preincubated for 15 mins measured after 15 mins by colorimetric Ellman assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Sepuluh Nopember Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50356915(GANODERIC ACID B)
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibition of recombinant human aldose reductase using dl-glyceraldehyde as substrate after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed