BDBM50354297 CHEMBL1836554

SMILES CC1=Nc2ccc(cc2[C@@H](N1CC(=O)OC)c3ccccc3)Br

InChI Key InChIKey=ZWSKQYINLNUCMK-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50354297   

TargetTrypanothione reductase(Trypanosoma cruzi)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50354297(CHEMBL1836554)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of trypanothione reductase from Trypanosoma cruzi by DTNB-coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50354297(CHEMBL1836554)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50354297(CHEMBL1836554)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by DTNB-coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)