BDBM50350803 CHEMBL1819131

SMILES COc1cc2c(cc1OCCc3ccc4ccccc4n3)c(ncn2)[N@]5CCC[C@H](C5)c6ccccc6

InChI Key InChIKey=MUQUFIBWWXZLNL-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350803   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Pfizer

Curated by ChEMBL

LigandBDBM50350803(CHEMBL1819131)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant rat PDE10A expressed in Sf9 cells using [3H]cAMP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/23/2012
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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