BDBM50350798 CHEMBL1738857

SMILES COc1cc2cncnc2cc1OCCc3ccc4ccccc4n3

InChI Key InChIKey=REIGRVDNVZOVDL-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50350798   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Pfizer

Curated by ChEMBL

LigandBDBM50350798(CHEMBL1738857)Copy SMILESCopy InChI

Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant rat PDE10A expressed in Sf9 cells using [3H]cAMP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/23/2012
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL