BDBM50347657 CHEMBL1615181

SMILES O=C(CCc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(c1)C1CCNCC1)NCc1ccccn1

InChI Key InChIKey=PCKOOTOQVCFRHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347657   

TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50347657(CHEMBL1615181)
Affinity DataIC50: 85nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50347657(CHEMBL1615181)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50347657(CHEMBL1615181)
Affinity DataIC50: 28nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed