BDBM50347499 CHEMBL1802335::hsp90_4

SMILES c1ccc2c(c1)NC(=O)N2c3ccc(cc3O)O

InChI Key InChIKey=VCZFDVVMKKLXAN-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347499   

TargetHeat shock protein HSP 90-beta(Human)
D3R/Abbott

LigandPNGBDBM50347499(CHEMBL1802335 | hsp90_4)
Affinity DataIC50: 220nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347499(CHEMBL1802335 | hsp90_4)
Affinity DataIC50: 220nMAssay Description:Binding affinity to Hsp90alpha N-terminal ATPase domain by TR-FRET assay based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347499(CHEMBL1802335 | hsp90_4)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of Hsp90alpha ATPase activity by malachite green ATP-ase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed