BDBM50347389 CHEMBL1801932

SMILES CC(C)c1cnn2c1nc(cc2NCc3ccccc3)NCCCCCCN

InChI Key InChIKey=DNYBIOICMDTDAP-UHFFFAOYSA-N

Data  23 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50347389   

TargetCyclin-dependent kinase 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 3.30E+4nMAssay Description:Competitive reversible inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 880nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 5(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 3.00E+3nMAssay Description:Competitive reversible inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 900nMAssay Description:Competitive reversible inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 4.20E+3nMAssay Description:Competitive reversible inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 4.70E+4nMAssay Description:Competitive reversible inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 7(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 21nMAssay Description:Competitive reversible inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 1(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 4.47E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 134nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) expressed in sf9 cells using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Lebanese American University

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CDK5 (unknown origin) using histone H1 as substrate in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 4.47E+4nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) using RPPTLSPIPHIPR peptide as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CDK5/p35NCK (unknown origin) using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed