BDBM50343933 2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid::CHEMBL1235556

SMILES c1cc2c(cn(c2nc1)CC(=O)O)Cc3nc4c(c(cc(c4s3)F)F)F

InChI Key InChIKey=IEVFQDJUDLCOQY-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343933   

TargetAldo-keto reductase family 1 member B1(Human)
The Institute For Diabetes Discovery

Curated by ChEMBL
LigandPNGBDBM50343933(2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant aldose reductase 1 after 10 mins by spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)