BDBM50342655 2-ethyl-1H-indene::CHEMBL1770734

SMILES c1ccc2c(c1)nc(s2)CN

InChI Key InChIKey=VLBUERZRFSORRZ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342655   

TargetAcid-sensing ion channel 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342655(2-ethyl-1H-indene | CHEMBL1770734)
Affinity DataIC50: 3.63E+5nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetUbiquitin-conjugating enzyme E2 T(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50342655(2-ethyl-1H-indene | CHEMBL1770734)
Affinity DataKd:  1.30E+6nMAssay Description:Binding affinity to full length N-terminal 6xHis-Smt3 tagged human Ube2T expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)