BDBM50335100 1,3-benzothiazol-2-amine::2-Aminobenzothiazole, 6::Benzothiazol-2-ylamine::CHEMBL329785::benzo[d]thiazol-2-amine

SMILES c1ccc2c(c1)nc(s2)N

InChI Key InChIKey=UHGULLIUJBCTEF-UHFFFAOYSA-N

Data  2 KI  3 IC50  1 Kd

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50335100   

TargetDNA repair and recombination protein RadA(Pyrococcus furiosus)
University of Cambridge

LigandPNGBDBM50335100(Benzothiazol-2-ylamine | 2-Aminobenzothiazole, 6 |...)
Affinity DataKd:  7.30E+5nMAssay Description:The thermal-shift denaturation assay was performed on an iCycler iQ Real Time Detection System (BioRad) in 96-well iCycler iQ PCR plates sealed with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335100(Benzothiazol-2-ylamine | 2-Aminobenzothiazole, 6 |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50335100(Benzothiazol-2-ylamine | 2-Aminobenzothiazole, 6 |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPteridine reductase 1(Leishmania major)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50335100(Benzothiazol-2-ylamine | 2-Aminobenzothiazole, 6 |...)
Affinity DataIC50: 1.80E+6nMAssay Description:Inhibition of Leishmania major PTR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetPteridine reductase 1(Leishmania major)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50335100(Benzothiazol-2-ylamine | 2-Aminobenzothiazole, 6 |...)
Affinity DataKi:  1.43E+5nMAssay Description:Inhibition of Leishmania major PTR1 by Lineweaver-Burk analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50335100(Benzothiazol-2-ylamine | 2-Aminobenzothiazole, 6 |...)
Affinity DataKi: >2.00E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed