BDBM50331612 CHEMBL1290072::N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine

SMILES COc1ccc(CNc2ccnc3oc4ccccc4c23)cc1

InChI Key InChIKey=MNMQBQOLMHVBJT-UHFFFAOYSA-N

Data  22 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 50331612   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of human CDK6/Cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 3.76E+5nMAssay Description:Inhibition of human CDK4/Cyclin D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 6.22E+5nMAssay Description:Inhibition of human InsRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 3.92E+5nMAssay Description:Inhibition of human ABL1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 2.71E+5nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInsulin receptor-related protein(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibition of human InsRRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase VRK1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of human VRK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataIC50: 7.59E+5nMAssay Description:Inhibition of human LIMK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi:  150nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi:  400nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human WEE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL2(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human ABL2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human INK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human PDGFR-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek3(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human Nek3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human IRAK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human CK1-alpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human DYRK1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human HIPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase C(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human Aurora CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human PKC-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human ERK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetProtein kinase C iota type(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human PKC-iotaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50331612(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of human p38-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed