BDBM50329018 (2-(3-fluoro-2-methylbenzyl)-5-hydroxy-4-methyl-1-phenyl-1H-indol-3-yl)(piperazin-1-yl)methanone::2-(3-fluoro-2-methylbenzyl)-4-methyl-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indol-5-ol::CHEMBL1236060

SMILES Cc1c(cccc1F)Cc2c(c3c(c(ccc3n2c4ccccc4)O)C)C(=O)N5CCNCC5

InChI Key InChIKey=LWFGTVRNQYOUHL-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329018   

TargetRenin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50329018((2-(3-fluoro-2-methylbenzyl)-5-hydroxy-4-methyl-1-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant renin using fluorogenic substrate by microplate spectrofluorimeterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)