BDBM50328766 1-(3-tert-butyl-1-(4-(hydroxymethyl)phenyl)-1H-pyrazol-5-yl)-3-(naphthalen-1-yl)urea::CHEMBL1271167

SMILES CC(C)(C)c1cc(n(n1)c2ccc(cc2)CO)NC(=O)Nc3cccc4c3cccc4

InChI Key InChIKey=MKYJHFRHAZBFKJ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328766   

TargetMitogen-activated protein kinase 14(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328766(1-(3-tert-butyl-1-(4-(hydroxymethyl)phenyl)-1H-pyr...)
Affinity DataIC50: 27nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)