BDBM50326776 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE::CHEMBL549789::Ponasterone A

SMILES CC(C)CC[C@H]([C@@](C)([C@H]1CC[C@@]2([C@@]1(CC[C@H]3C2=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)C)O)O)O

InChI Key InChIKey=PJYYBCXMCWDUAZ-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50326776   

TargetEcdysone receptor(Green bottle fly)
Csiro Molecular and Health Technologies

Curated by ChEMBL
LigandPNGBDBM50326776(2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | Pona...)
Affinity DataIC50: 900nMAssay Description:Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetEcdysone receptor(Fruit fly)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50326776(2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | Pona...)
Affinity DataIC50: 1.29nMAssay Description:Binding affinity to ecdysone receptor ligand binding domain in Drosophila melanogaster assessed as number of hydrogen bonds formedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetUltraspiracle(Southern green stink bug)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50326776(2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | Pona...)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]PonA from recombinant Nezara viridula EcR11More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetUltraspiracle(Southern green stink bug)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50326776(2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | Pona...)
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]PonA from recombinant Nezara viridula EcR10More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetUltraspiracle(Southern green stink bug)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50326776(2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | Pona...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]PonA from recombinant Nezara viridula EcR11More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetUltraspiracle(Southern green stink bug)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50326776(2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | Pona...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]PonA from recombinant Nezara viridula EcR10More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed