BDBM50324922 (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(cyclohexylmethyl)pentanamide::(S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(cyclohexylmethyl)pentanamide::CHEMBL1222240

SMILES CC[C@@H](CC(=O)NCC1CCCCC1)n2c3ccc(cc3nc2N)Cl

InChI Key InChIKey=UKACQFCXAAAWAE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324922   

TargetBeta-secretase 1(Human)
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Evotec

Curated by ChEMBL
LigandPNGBDBM50324922((3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human BACE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed