BDBM50324678 CHEMBL1222314::thiophene-2-carboxylic acid

SMILES c1cc(sc1)C(=O)O

InChI Key InChIKey=QERYCTSHXKAMIS-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324678   

TargetD-amino-acid oxidase(Human)
Tokushima University

Curated by ChEMBL

LigandBDBM50324678(thiophene-2-carboxylic acid | CHEMBL1222314)Copy SMILESCopy InChI

Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human DAO using D-serine as substrate after 20 mins in presence of FADMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/18/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetBeta-lactamase(Escherichia coli (strain K12))
TBA

Curated by ChEMBL

LigandBDBM50324678(thiophene-2-carboxylic acid | CHEMBL1222314)Copy SMILESCopy InChI

Affinity DataKi:  4.00E+7nMAssay Description:Inhibition of Escherichia coli AmpC assessed as nitrocefin hydrolysis by UV-Vis spectrophotometryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/20/2011
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL