BDBM50323722 4-fluorophenyl 3-(4-hydroxy-3,5-dimethylstyryl)benzoate::4-fluorophenyl 3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoate::CHEMBL1213031

SMILES Cc1cc(cc(c1O)C)\C=C\c2cccc(c2)C(=O)Oc3ccc(cc3)F

InChI Key InChIKey=YDSMVVNYVJZDET-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323722   

TargetTransthyretin(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50323722(4-fluorophenyl 3-[(E)-2-(4-hydroxy-3,5-dimethylphe...)
Affinity DataIC50: 1.96E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)