BDBM50317512 Aesculioside IIIc::CHEMBL1095341

SMILES CCC(C)C(=O)O[C@H]1[C@H](OC(=O)C(\C)=C\C)C(C)(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O)[C@H](O[C@@H]7O[C@@H](CO)[C@H](O)[C@H]7O)[C@H]6O[C@@H]6O[C@H](CO)[C@H](O)[C@H](O)[C@H]6O)C(O)=O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)[C@@H](O)[C@@H](O)[C@@]12CO

InChI Key InChIKey=LPHWHWVLCPLJNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317512   

TargetDNA topoisomerase 1(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317512(Aesculioside IIIc | CHEMBL1095341)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50317512(Aesculioside IIIc | CHEMBL1095341)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed