BDBM50316350 2-(5-{[(2R)-2-Amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c]-2,7-naphthyridin-4-amine::2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine::CHEMBL1095294

SMILES COc1cc2ncc3c(N)nc(cc3c2cc1OC)-c1cncc(OC[C@H](N)Cc2ccccc2)c1

InChI Key InChIKey=XNXUJUXYVTYIGP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316350   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316350(2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316350(2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 259nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316350(2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 88nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed