BDBM50311742 8-DEOXYGARTANIN::8-desoxygartanin::CHEMBL488606

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2oc3c(-[#8])cccc3c(=O)c2c1-[#8]

InChI Key InChIKey=BOSWOTVHBKLIRP-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311742   

TargetNuclear factor NF-kappa-B p105 subunit(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311742(CHEMBL488606 | 8-desoxygartanin | 8-DEOXYGARTANIN)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50311742(CHEMBL488606 | 8-desoxygartanin | 8-DEOXYGARTANIN)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50311742(CHEMBL488606 | 8-desoxygartanin | 8-DEOXYGARTANIN)
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50311742(CHEMBL488606 | 8-desoxygartanin | 8-DEOXYGARTANIN)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant C-terminal 6xHis-tagged MTH1 (3 to 156 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50311742(CHEMBL488606 | 8-desoxygartanin | 8-DEOXYGARTANIN)
Affinity DataKi:  1.55E+4nMAssay Description:Competitive inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed