BDBM50309916 3-oxo-2-(piperidin-4-yl)isoindoline-4-carboxamide::3-oxo-2-piperidin-4-yl-2,3-dihydro-1H-isoindole-4-carboxamide::CHEMBL597890

SMILES c1cc2c(c(c1)C(=O)N)C(=O)N(C2)C3CCNCC3

InChI Key InChIKey=KISOFIKBJFDVKM-UHFFFAOYSA-N

Data  1 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309916   

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50309916(3-oxo-2-piperidin-4-yl-2,3-dihydro-1H-isoindole-4-...)
Affinity DataEC50:  51nMAssay Description:Inhibition of PARP1 in human C41 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50309916(3-oxo-2-piperidin-4-yl-2,3-dihydro-1H-isoindole-4-...)
Affinity DataKi:  33nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)