BDBM50307869 (S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)pyrrolidine-2-carboxamide hydrochloride::CHEMBL597201

SMILES [H]/N=C(/c1ccc(cc1)CNC(=O)[C@@H]2CCCN2C(=O)CCc3ccccc3)N

InChI Key InChIKey=RNZKCCPFUWHBFY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307869   

TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307869((S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl...)
Affinity DataKi:  220nMAssay Description:Inhibition of human alpha-thrombin using tPa (CH3SO2-D-Cha-Gly-Arg-pNA.AcOH) as chromogenic substrate by kinetic photometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307869((S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl...)
Affinity DataKi:  720nMAssay Description:Inhibition of thrombin (unknown origin) using CH3SO2-D-Cha-Gly-Arg-pNA.AcOH as substrate measured every 20 sec for 30 mins in presence of NaCl by UV-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50307869((S)-N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl...)
Affinity DataKi:  750nMAssay Description:Binding affinity to human thrombin by standard kinetic photometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed