BDBM50305565 CHEMBL590361::N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide

SMILES Cc1cc(sc1CCOC)S(=O)(=O)NC(=O)Nc2ncc(s2)Br

InChI Key InChIKey=GYLXXAGXBDRUHI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305565   

TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305565(N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethyl...)
Affinity DataIC50: 60nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305565(N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethyl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305565(N-(5-bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethyl...)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)