BDBM50304855 4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one::4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3H-pyrazol-3-one::CHEMBL606919

SMILES CN1C(=C(C(=O)N1C)c2cccc(c2)COC)c3ccc4c(c3)nccn4

InChI Key InChIKey=OWJLLMXRMBEWIM-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304855   

TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304855(4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinox...)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of TGFR-1 in human HepG2 cells expressing PAI-luciferase by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50304855(4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinox...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)