BDBM50304360 BENZENE-1,2,3,4-TETRAYL TETRAKIS[DIHYDROGEN (PHOSPHATE)]::CHEMBL595349::benzene-1,2,3,4-tetrayl tetrakis(hydrogen phosphate)

SMILES c1cc(c(c(c1OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O

InChI Key InChIKey=UKRGHRHHBNLNDD-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304360   

TargetInositol polyphosphate-5-phosphatase A(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50304360(benzene-1,2,3,4-tetrayl tetrakis(hydrogen phosphat...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Human)
School of Biological Sciences, Uea

Curated by ChEMBL
LigandPNGBDBM50304360(benzene-1,2,3,4-tetrayl tetrakis(hydrogen phosphat...)
Affinity DataIC50: 2.78E+3nMAssay Description:Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304360(benzene-1,2,3,4-tetrayl tetrakis(hydrogen phosphat...)
Affinity DataKi:  80nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)