BDBM50299083 (S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2-yl)benzofuran::CHEMBL574613

SMILES CC[S@](=O)c1ccc(cc1)-c1coc2ccc(cc12)-c1ccc(C)o1

InChI Key InChIKey=NCGGCRHITOMNJS-UHFFFAOYSA-N

Data  23 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50299083   

TargetVascular endothelial growth factor receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged VEGFR2 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Kit by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Met by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TIE2 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalpha by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal peptide-tagged ERBB2 cytoplasmic domain by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal peptide-tagged EGFR cytoplasmic domain by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged CK1delta by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged IKK-beta by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged CHK1 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Lck by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged MEKK1 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged JNK1 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged p38alpha by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK5 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged CDK2 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged CDK1 by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299083((S)-3-(4-(ethylsulfinyl)phenyl)-5-(5-methylfuran-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptor by [gamma-33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed