BDBM50296004 2-(4-(5-(naphthalen-2-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)acetic acid::CHEMBL549906::[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid

SMILES c1ccc2cc(ccc2c1)c3cc4c(c[nH]c4nc3)c5ccc(cc5)CC(=O)O

InChI Key InChIKey=SWXKLXXVFMYMDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296004   

TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296004([4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50: 63nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50296004([4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-y...)
Affinity DataIC50: 880nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed