BDBM50294173 (4-fluorophenyl)(pyridin-4-yl)methanone::CHEMBL563196

SMILES c1cc(ccc1C(=O)c2ccncc2)F

InChI Key InChIKey=WTRWBYGUMQEFFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294173   

TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294173((4-fluorophenyl)(pyridin-4-yl)methanone | CHEMBL56...)
Affinity DataIC50: 3.67E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294173((4-fluorophenyl)(pyridin-4-yl)methanone | CHEMBL56...)
Affinity DataIC50: 5.31E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Decode Biostructures

Curated by ChEMBL
LigandPNGBDBM50294173((4-fluorophenyl)(pyridin-4-yl)methanone | CHEMBL56...)
Affinity DataIC50: 5.38E+6nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed