BDBM50293594 5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosphonic acid::CHEMBL495498

SMILES CC(C)Cc1sc(N)nc1-c1ccc(o1)P(O)(O)=O

InChI Key InChIKey=XJMYIJPPDSZOPN-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50293594   

TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human liver recombinant FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataEC50:  16nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) using FBP as substrate in presence of PGI and G6PDH by spectrophotometric me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed