BDBM50280934 1-tert-Butylamino-3-(thiochroman-8-yloxy)-propan-2-ol::1-tert-Butylamino-3-(thiochroman-8-yloxy)-propan-2-ol(TERtatolol)::CHEMBL434200::TERTATOLOL(-)::Tertatolol

SMILES CC(C)(C)NCC(O)COc1cccc2CCCSc12

InChI Key InChIKey=HTWFXPCUFWKXOP-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50280934   

Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  6.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  7.70nMAssay Description:The compound was evaluated for binding affinity against 5-hydroxytryptamine 1A receptor in rat hippocampal membranes using [3H]8-OH-DPAT as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  8.31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  19nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  38nMAssay Description:The compound was evaluated for binding affinity against 5-hydroxytryptamine 1A receptor in rat hippocampal membranes using [3H]8-OH-DPAT as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1B(Rat)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  182nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Pig)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  363nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi:  1.45E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50280934(TERTATOLOL(-) | 1-tert-Butylamino-3-(thiochroman-8...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2012
Entry Details
PubMed