BDBM50277229 CHEMBL4166541

SMILES Cc1cc(n(n1)Cc2ccc(cc2)C(=O)NCc3ccc(cc3Cl)F)C

InChI Key InChIKey=PUPDWYSTSLHVKJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277229   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50277229(CHEMBL4166541)
Affinity DataIC50: 40nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA using DDCoA as substrate in presence of NADH by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50277229(CHEMBL4166541)
Affinity DataKi:  50nMAssay Description:Inhibition of Mycobacterium tuberculosis InhAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)