BDBM50275665 5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidazo[1,5-f][1,2,4]triazin-2-amine::5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidazo[5,1-f][1,2,4]triazin-2-amine::CHEMBL519715

SMILES Cc1c2cnc(nn2c(n1)c3ccccc3)Nc4cc(c(c(c4)OC)OC)OC

InChI Key InChIKey=HOOQLZPFGONGJY-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275665   

TargetSerine/threonine-protein kinase PLK3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50: 90nMAssay Description:Inhibition of PLK3 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed