BDBM50273900 CHEMBL4128261

SMILES Cn1c2ccc(cc2cn1)c3ccc(cc3)C4=NC5(CC5)C(=O)N4C[C@@H]6CCN(C6)C(=O)C7CC7

InChI Key InChIKey=KYFZEWZCYBWMGN-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273900   

TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273900(CHEMBL4128261)
Affinity DataIC50: 30nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)