BDBM50271829 2-Propyl-isothiourea::CHEMBL483092

SMILES CCCSC(N)=N

InChI Key InChIKey=JKHAGQZCIAFTOX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271829   

TargetNitric oxide synthase, brain(Human)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50271829(2-Propyl-isothiourea | CHEMBL483092)
Affinity DataKi:  29nMAssay Description:Inhibition of nNOS in human DLD-1 cells assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Human)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50271829(2-Propyl-isothiourea | CHEMBL483092)
Affinity DataKi:  240nMAssay Description:Inhibition of iNOS in human DLD-1 cells assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetNitric oxide synthase, brain(Human)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50271829(2-Propyl-isothiourea | CHEMBL483092)
Affinity DataKi:  630nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50271829(2-Propyl-isothiourea | CHEMBL483092)
Affinity DataKi:  670nMAssay Description:Inhibition of eNOS in human DLD-1 cells assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed