BDBM50271275 1H-Indazol-7-amine::1H-indazol-7-amine, 1::CHEMBL463676

SMILES c1cc2cn[nH]c2c(c1)N

InChI Key InChIKey=OTFFCAGPSWJBDK-UHFFFAOYSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50271275   

TargetGenome polyprotein [1658-1692](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Astex Pharmaceuticals

LigandPNGBDBM50271275(1H-indazol-7-amine, 1 | CHEMBL463676 | 1H-Indazol-...)
Affinity DataIC50: 5.00E+6nMT: 2°CAssay Description:The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Rat)
Université

Curated by ChEMBL
LigandPNGBDBM50271275(1H-indazol-7-amine, 1 | CHEMBL463676 | 1H-Indazol-...)
Affinity DataIC50: 8.50E+5nMAssay Description:Inhibition of rat brain recombinant nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Université

Curated by ChEMBL
LigandPNGBDBM50271275(1H-indazol-7-amine, 1 | CHEMBL463676 | 1H-Indazol-...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM50271275(1H-indazol-7-amine, 1 | CHEMBL463676 | 1H-Indazol-...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Uned

Curated by ChEMBL
LigandPNGBDBM50271275(1H-indazol-7-amine, 1 | CHEMBL463676 | 1H-Indazol-...)
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of recombinant NOS1 assessed as citrulline formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed