BDBM50267521 3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxybenzofuran-3-yl)pyrrole-2,5-dione::CHEMBL523435

SMILES Cn1cc(c2c1cc(c(c2)F)I)C3=C(C(=O)NC3=O)c4coc5c4cccc5OC

InChI Key InChIKey=JBKILIGSDAQHSL-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50267521   

TargetCyclin-dependent kinase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: 247nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50267521(3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-me...)
Affinity DataIC50: 247nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)