BDBM50267510 (3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluylphenylethyl)-piperidine-4-yl)-methanol::CHEMBL476839

SMILES COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccc(C)cc2)CC1

InChI Key InChIKey=MJKRYUCQHJLOIV-UHFFFAOYSA-N

Data  24 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50267510   

Target5-hydroxytryptamine receptor 2A(Rat)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  1.83nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  143nMAssay Description:Inhibition of human cloned Alpha-2C adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  439nMAssay Description:Inhibition of human cloned histamine H1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  466nMAssay Description:Inhibition of human cloned 5HT2B receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  498nMAssay Description:Inhibition of human cloned 5HT7 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  508nMAssay Description:Inhibition of human cloned 5-HT2C receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of human cloned histamine H2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  1.44E+3nMAssay Description:Inhibition of human cloned 5HT1D receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  1.76E+3nMAssay Description:Inhibition of human cloned dopamine D1 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  2.65E+3nMAssay Description:Inhibition of human cloned SERT by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  2.71E+3nMAssay Description:Inhibition of human cloned dopamine D4 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi:  4.89E+3nMAssay Description:Inhibition of human cloned 5HT1B receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned beta3 adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT1E receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned histamine H3 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT5A receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned dopamine D2 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT1A receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned mu opioid receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned DAT by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned alpha2A adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned Alpha-1B adrenergic receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz

Curated by ChEMBL
LigandPNGBDBM50267510((3-(2-Fluoroethoxy)-2-methoxyphenyl)-(1-(2-p-toluy...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cloned 5HT6 receptor by competitive binding experimentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed