BDBM50267086 Adociaquinone B::CHEMBL476648

SMILES C[C@@]12CCCc3coc(c13)C(=O)c1cc3C(=O)C4=NCCS(=O)(=O)C4C(=O)c3cc21

InChI Key InChIKey=LBOQXMUUCSVOMQ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50267086   

TargetM-phase inducer phosphatase 2(Human)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 80nMAssay Description:Inhibition of histidine-tagged full length human Cdc25B expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 110nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Mouse)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Rat)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of histidine-tagged rat recombinant MKP3 catalytic domain expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 70nMAssay Description:Inhibition of Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 200nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed