BDBM50263773 1-(2-naphthoyl)-3-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yl)urea::CHEMBL490001::N-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-ylcarbamoyl)-2-naphthamide

SMILES c1ccc2cc(ccc2c1)C(=O)NC(=O)N[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

InChI Key InChIKey=CWTXJPICSREUOK-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50263773   

TargetGlycogen phosphorylase, muscle form(Rabbit)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50263773(1-(2-naphthoyl)-3-((2R,3R,4S,5S,6R)-3,4,5-trihydro...)
Affinity DataKi:  350nMAssay Description:Inhibition of rabbit skeletal muscle glycogen phosphorylase b assessed as inorganic phosphate releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen phosphorylase, muscle form(Rabbit)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50263773(1-(2-naphthoyl)-3-((2R,3R,4S,5S,6R)-3,4,5-trihydro...)
Affinity DataKi:  350nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen phosphorylase, muscle form(Rabbit)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50263773(1-(2-naphthoyl)-3-((2R,3R,4S,5S,6R)-3,4,5-trihydro...)
Affinity DataKi:  350nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen phosphorylase, muscle form(Rabbit)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50263773(1-(2-naphthoyl)-3-((2R,3R,4S,5S,6R)-3,4,5-trihydro...)
Affinity DataKi:  350nMpH: 6.8Assay Description:Inhibition of rabbit muscle glycogen phosphorylase b assessed as inorganic phosphate release at pH 6.8More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen phosphorylase, muscle form(Rabbit)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50263773(1-(2-naphthoyl)-3-((2R,3R,4S,5S,6R)-3,4,5-trihydro...)
Affinity DataKi:  350nMAssay Description:Inhibition of rabbit skeletal muscle glycogen phosphorylase b by Lineweaver-Burk plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)