BDBM50262987 CHEMBL506661::Illudalic acid

SMILES CC1(C)Cc2c(C1)c1C(=O)OC(O)Cc1c(C=O)c2O

InChI Key InChIKey=BDEDPKFUFGCVCJ-UHFFFAOYSA-N

Data  2 KI  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50262987   

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TCPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPep (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PTPmu (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CD45 (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PTPep (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of LAR (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LMWPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VHR (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HePTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant LARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PTPmu (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LMWPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VHR (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TCPTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CD45 (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of LAR (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HePTP (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataKi:  1.30E+5nMAssay Description:Non-covalent inhibition of LAR (unknown origin) using DiFMUP as substrate incubated for 15 to 120 mins followed by substrate addition at pH 6.5 by st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50262987(Illudalic acid | CHEMBL506661)
Affinity DataKi:  1.30E+5nMAssay Description:Non-covalent inhibition of LAR (unknown origin) using DiFMUP as substrate incubated for 15 to 120 mins followed by substrate addition at pH 6.5 by st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed