BDBM50262800 2-(2-chloro-6-fluorophenyl)ethylamine::CHEMBL452901

SMILES c1cc(c(c(c1)Cl)CCN)F

InChI Key InChIKey=NNEMMAAHBKHXLP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262800   

TargetTrace amine-associated receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50262800(2-(2-chloro-6-fluorophenyl)ethylamine | CHEMBL4529...)
Affinity DataEC50:  312nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50262800(2-(2-chloro-6-fluorophenyl)ethylamine | CHEMBL4529...)
Affinity DataIC50: 2.10E+6nMAssay Description:Inhibition of HIV-1 reverse transcriptase RT52A mutant using ABTS as substrate preincubated with compound for 1 hr followed by template-primer additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)