BDBM50262397 CHEMBL4074103

SMILES c1cc(ccc1c2cc3c(ccnc3[nH]2)C#N)N4CCNCC4

InChI Key InChIKey=NVTWXXPKCOGVMK-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50262397   

TargetSerine/threonine-protein kinase pim-1(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262397(CHEMBL4074103)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in full length human BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262397(CHEMBL4074103)
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed
TargetCell division cycle 7-related protein kinase(Human)
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50262397(CHEMBL4074103)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2020
Entry Details Article
PubMed