BDBM50259910 CHEMBL4097892

SMILES CN1C[C@H](C[C@@H]2[C@@H]1Cc3cccc(c3C2)OC)Cc4cccc(c4)OC

InChI Key InChIKey=QZUPQRHYHMMHGC-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259910   

TargetPolycomb protein EED(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50259910(CHEMBL4097892)
Affinity DataIC50: 2.50E+3nMAssay Description:Binding affinity to human methionine-13Cepsilon-methyl labeled PRC2-EED (76 to 441 residues) expressed in Escherichia coli BL21 (DE3) by 2D NMR metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolycomb protein EED(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50259910(CHEMBL4097892)
Affinity DataIC50: 890nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPolycomb protein EED(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50259910(CHEMBL4097892)
Affinity DataIC50: 890nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)