BDBM50258266 CHEMBL4088107

SMILES CC[C@H](c1ccc(cc1)OC(F)(F)F)NC(=O)c2cnn3c2ncc(c3)C

InChI Key InChIKey=CXEGBNQZVKLHTO-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258266   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258266(CHEMBL4088107)
Affinity DataIC50: 53nMAssay Description:Inhibition of PDE2A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258266(CHEMBL4088107)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)