BDBM50257213 CHEMBL2325016

SMILES c1cc(c(cc1S(=O)(=O)Nc2nccs2)C#N)Oc3ccc(cc3c4c[nH]nc4)Cl

InChI Key InChIKey=XPZRWGQUAVWXIG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257213   

TargetCytochrome P450 2C9(Human)
Icagen

Curated by ChEMBL
LigandPNGBDBM50257213(CHEMBL2325016)
Affinity DataIC50: 36nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50257213(CHEMBL2325016)
Affinity DataIC50: 31nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50257213(CHEMBL2325016)
Affinity DataIC50: 9nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed