BDBM50252375 CHEMBL446072::Spheciosterol sulfate C

SMILES C[C@H](CCC(C)C(C)(C)C(C)=C)[C@H]1CC[C@@]2(C)[C@@H]3C[C@H](OS([O-])(=O)=O)[C@H]4[C@@H](O)[C@H](OS([O-])(=O)=O)[C@H](C[C@]4(C)C3=CC[C@]12C)OS([O-])(=O)=O

InChI Key InChIKey=DETNYAODLCRBJF-UHFFFAOYSA-K

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252375   

TargetProtein kinase C zeta type(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(Spheciosterol sulfate C | CHEMBL446072)
Affinity DataIC50: 110nMAssay Description:Inhibition of PKCzeta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252375(Spheciosterol sulfate C | CHEMBL446072)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NF-kappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed