BDBM50248245 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid::CHEMBL516023

SMILES c1cc(cc(c1)C(=O)N)Cn2c3c(c4c2c(ccc4)C(=O)O)CCCCC3

InChI Key InChIKey=GKBQRPKZHUFGOB-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248245   

TargetFatty acid-binding protein, adipocyte(Human)
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50248245(5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocycloh...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human A-FABP by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFatty acid-binding protein, heart(Human)
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50248245(5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocycloh...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human H-FABP by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50248245(5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocycloh...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human A-FABP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFatty acid-binding protein, heart(Human)
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50248245(5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocycloh...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human H-FABP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed