BDBM50242462 CHEMBL4085721

SMILES c1ccc2c(c1)cc(n2CC(=O)NCc3ccccn3)c4cccs4

InChI Key InChIKey=HTRIQCMSXMSDKF-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242462   

TargetNT-3 growth factor receptor(Human)
Merck

Curated by ChEMBL

LigandBDBM50242462(CHEMBL4085721)Copy SMILESCopy InChI

Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of TrkC (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
10/15/2019
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetHigh affinity nerve growth factor receptor(Human)
Merck

Curated by ChEMBL

LigandBDBM50242462(CHEMBL4085721)Copy SMILESCopy InChI

Affinity DataIC50: 607nMAssay Description:Inhibition of PK-tagged human Trkalpha expressed in human U2OS cells assessed as reduction in beta NGF-induced EA-tagged SHC1 recruitment pretreated ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
10/15/2019
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL