BDBM50242419 6-Deoxy-L-galactose::6-deoxy-L-galactopyranoseL-fucopyranose::CHEMBL469449::L-fucopyranose::L-fucose

SMILES C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O

InChI Key InChIKey=SHZGCJCMOBCMKK-UHFFFAOYSA-N

Data  3 KI  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50242419   

TargetCD209 antigen(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataIC50: 2.95E+6nMAssay Description:Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataIC50: 910nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (HIPS)

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PAO1 LecA assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTissue alpha-L-fucosidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataKi:  3.00E+5nMAssay Description:Compound was tested for inhibitory activity (competitive) against alpha-L-fucosidase from bovine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetTissue alpha-L-fucosidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition constant against Alpha-Fucosidase; Uncompetitive inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2012
Entry Details Article

TargetCD209 antigen(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50242419(6-deoxy-L-galactopyranoseL-fucopyranose | L-fucopy...)
Affinity DataKi:  6.70E+6nMAssay Description:Displacement of [125I]-Man30-BSA from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by gamma-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed